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Decision to follow completion of Phase Ib trial for LTI-291
January 9, 2017
By: Kristin Brooks
Managing Editor, Contract Pharma
Allergan has purchased an exclusive option right to acquire Lysosomal Therapeutics (LTI), a drug developer focused on small-molecule R&D in the field of neurodegeneration. LTI’s lead program, LTI-291, aims to stimulate the activity of glucocerebrosidase (GCase) in the brain. In several lysosomal storage diseases, the activity of GCase is reduced due to genetic mutations in the GBA1 gene. Approximately 5 to 10 percent of patients with Parkinson’s disease (PD) have mutations of...
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